DNA-Based Sensor Particles Enable Measuring Light Intensity in Single Cells

© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 28(2016), 14 vom: 13. Apr., Seite 2765-70
1. Verfasser: Mikutis, Gediminas (VerfasserIn)
Weitere Verfasser: Mora, Carlos A, Puddu, Michela, Paunescu, Daniela, Grass, Robert N, Stark, Wendelin J
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't caged oligonucleotides light sensors nanosensor sensor particles single cell analysis 6-nitropiperonyloxymethyl chloride Dioxoles DNA 9007-49-2
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520 |a "Lab on a particle" architecture is employed in designing a light nanosensor. Light-sensitive protecting groups are installed on DNA, which is encapsulated in silica particles, qualifying as a self-sufficient light sensor. The nanosensors allow measuring light intensity and duration in very small volumes, such as single cells, and store the irradiation information until readout 
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650 4 |a single cell analysis 
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700 1 |a Puddu, Michela  |e verfasserin  |4 aut 
700 1 |a Paunescu, Daniela  |e verfasserin  |4 aut 
700 1 |a Grass, Robert N  |e verfasserin  |4 aut 
700 1 |a Stark, Wendelin J  |e verfasserin  |4 aut 
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