DNA-Based Sensor Particles Enable Measuring Light Intensity in Single Cells

© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 28(2016), 14 vom: 13. Apr., Seite 2765-70
1. Verfasser: Mikutis, Gediminas (VerfasserIn)
Weitere Verfasser: Mora, Carlos A, Puddu, Michela, Paunescu, Daniela, Grass, Robert N, Stark, Wendelin J
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't caged oligonucleotides light sensors nanosensor sensor particles single cell analysis 6-nitropiperonyloxymethyl chloride Dioxoles DNA 9007-49-2
Beschreibung
Zusammenfassung:© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
"Lab on a particle" architecture is employed in designing a light nanosensor. Light-sensitive protecting groups are installed on DNA, which is encapsulated in silica particles, qualifying as a self-sufficient light sensor. The nanosensors allow measuring light intensity and duration in very small volumes, such as single cells, and store the irradiation information until readout
Beschreibung:Date Completed 21.12.2016
Date Revised 30.09.2020
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201504892