The MMP-1/PAR-1 Axis Enhances Proliferation and Neuronal Differentiation of Adult Hippocampal Neural Progenitor Cells

Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that play a role in varied forms of developmental and postnatal neuroplasticity. MMP substrates include protease-activated receptor-1 (PAR-1), a G-protein coupled receptor expressed in hippocampus. We examined proliferation and diffe...

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Publié dans:	Neural plasticity. - 1998. - 2015(2015) vom: 01., Seite 646595
Auteur principal:	Valente, Maria Maddalena (Auteur)
Autres auteurs:	Allen, Megan, Bortolotto, Valeria, Lim, Seung T, Conant, Katherine, Grilli, Mariagrazia
Format:	Article en ligne
Langue:	English
Publié:	2015
Accès à la collection:	Neural plasticity
Sujets:	Journal Article Research Support, N.I.H., Extramural NF-kappa B Receptor, PAR-1 SOXB1 Transcription Factors Sox2 protein, mouse Matrix Metalloproteinase 13 EC 3.4.24.- Mmp13 protein, mouse