The MMP-1/PAR-1 Axis Enhances Proliferation and Neuronal Differentiation of Adult Hippocampal Neural Progenitor Cells
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that play a role in varied forms of developmental and postnatal neuroplasticity. MMP substrates include protease-activated receptor-1 (PAR-1), a G-protein coupled receptor expressed in hippocampus. We examined proliferation and diffe...
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Bibliographische Detailangaben
| Veröffentlicht in: | Neural plasticity. - 1998. - 2015(2015) vom: 01., Seite 646595
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| 1. Verfasser: |
Valente, Maria Maddalena
(VerfasserIn) |
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| Weitere Verfasser: |
Allen, Megan,
Bortolotto, Valeria,
Lim, Seung T,
Conant, Katherine,
Grilli, Mariagrazia |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2015
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| Zugriff auf das übergeordnete Werk: | Neural plasticity
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| Schlagworte: | Journal Article
Research Support, N.I.H., Extramural
NF-kappa B
Receptor, PAR-1
SOXB1 Transcription Factors
Sox2 protein, mouse
Matrix Metalloproteinase 13
EC 3.4.24.-
Mmp13 protein, mouse |
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