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231224s2016 xx |||||o 00| ||eng c |
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|a 10.1002/adma.201505524
|2 doi
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|a eng
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1 |
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|a Wu, Meiying
|e verfasserin
|4 aut
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|a Large Pore-Sized Hollow Mesoporous Organosilica for Redox-Responsive Gene Delivery and Synergistic Cancer Chemotherapy
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|c 2016
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|a Text
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|a ƒaComputermedien
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|a Date Completed 13.12.2016
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|a Date Revised 18.03.2022
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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|a A stability-difference-selective bond-breakage strategy for the fabrication of largepore-sized hollow mesoporous organosilica nanoparticles (HMONs) is successfully developed. Moreover, surfacefunctionalized HMONs are successfully constructed to simultaneously deliver P-gp modulator siRNA and anticancer drug doxorubicin to reverse the multidrug resistance of cancer cells
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a cancer therapy
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|a gene delivery
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|a large pores
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|a multidrug resistance
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|a nanoparticles
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|a Antineoplastic Agents
|2 NLM
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|a Metals
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| 700 |
1 |
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|a Meng, Qingshuo
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|a Chen, Yu
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| 700 |
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|a Zhang, Lingxia
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|a Li, Mengli
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|a Cai, Xiaojun
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| 700 |
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|a Li, Yaping
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| 700 |
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|a Yu, Pengcheng
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|a Zhang, Linlin
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|a Shi, Jianlin
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