Binding of Folic Acid Induces Specific Self-Aggregation of Lactoferrin : Thermodynamic Characterization

In the study presented here, we investigated the interaction at pH 5.5 between folic acid (FA) and lactoferrin (LF), a positively charged protein. We found a binding constant Ka of 10(5) M(-1) and a high stoichiometry of 10 mol of FA/mol of LF. The size and charge of the complexes formed evolved dur...

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Publié dans:	Langmuir : the ACS journal of surfaces and colloids. - 1985. - 31(2015), 45 vom: 17. Nov., Seite 12481-8
Auteur principal:	Tavares, Guilherme M (Auteur)
Autres auteurs:	Croguennec, Thomas, Lê, Sébastien, Lerideau, Olivia, Hamon, Pascaline, Carvalho, Antônio F, Bouhallab, Saïd
Format:	Article en ligne
Langue:	English
Publié:	2015
Accès à la collection:	Langmuir : the ACS journal of surfaces and colloids
Sujets:	Journal Article Research Support, Non-U.S. Gov't LTF protein, human Protein Aggregates Folic Acid 935E97BOY8 Lactoferrin EC 3.4.21.-