The Characteristics and Short-term Refractive Error Outcomes of Cystoid Macular Edema in Premature Neonates as Detected by Spectral-Domain Optical Coherence Tomography

Copyright 2015, SLACK Incorporated.

Bibliographische Detailangaben
Veröffentlicht in:Ophthalmic surgery, lasers & imaging retina. - 2013. - 46(2015), 8 vom: 27. Sept., Seite 806-12
1. Verfasser: Bondalapati, Sailaja (VerfasserIn)
Weitere Verfasser: Milam, Ronald W Jr, Ulrich, J Niklas, Cabrera, Michelle T
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Ophthalmic surgery, lasers & imaging retina
Schlagworte:Journal Article Observational Study Research Support, Non-U.S. Gov't Angiogenesis Inhibitors VEGFA protein, human Vascular Endothelial Growth Factor A Bevacizumab 2S9ZZM9Q9V
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100 1 |a Bondalapati, Sailaja  |e verfasserin  |4 aut 
245 1 4 |a The Characteristics and Short-term Refractive Error Outcomes of Cystoid Macular Edema in Premature Neonates as Detected by Spectral-Domain Optical Coherence Tomography 
264 1 |c 2015 
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500 |a Citation Status MEDLINE 
520 |a Copyright 2015, SLACK Incorporated. 
520 |a BACKGROUND AND OBJECTIVE: To explore characteristics associated with cystoid macular edema (CME) in neonates screened for retinopathy of prematurity (ROP) 
520 |a PATIENTS AND METHODS: In this institutional review board-approved, prospective, observational study, premature neonates underwent imaging with handheld spectral-domain optical coherence tomography 
520 |a RESULTS: Of 73 included infants (median gestational age [GA]: 28 weeks, range 23-33 weeks; birth weight: 966 g, range 506 g-1695 g), 28 (38%) had CME and 17/28 (61%) had ROP. CME was associated with ROP (P=.03) and younger GA (P=.04), but not associated with sex, race, birth weight, postmenstrual age at imaging, ROP severity, or myopia at median 6 months corrected age. CME resolved in three cases after bevacizumab treatment for type 1 ROP and in five cases without treatment. CME appeared in two cases several weeks following injections 
520 |a CONCLUSION: CME was associated with ROP and younger GA, but not with myopia. Intravitreal bevacizumab for type 1 ROP has inconclusive effects on CME 
650 4 |a Journal Article 
650 4 |a Observational Study 
650 4 |a Research Support, Non-U.S. Gov't 
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700 1 |a Milam, Ronald W  |c Jr  |e verfasserin  |4 aut 
700 1 |a Ulrich, J Niklas  |e verfasserin  |4 aut 
700 1 |a Cabrera, Michelle T  |e verfasserin  |4 aut 
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