Morphology-dependent antimicrobial activity of Cu/CuxO nanoparticles

Cu/CuxO nanoparticles (NPs) with different morphologies have been synthesized with glucose as a reducing agent. The X-ray diffraction and Scanning electron microscopy imaging show that the Cu/CuxO NPs have fine crystalline peaks with homogeneous polyhedral, flower-like, and thumbtack-like morphologi...

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Veröffentlicht in:Ecotoxicology (London, England). - 1992. - 24(2015), 10 vom: 25. Dez., Seite 2067-72
1. Verfasser: Xiong, Lu (VerfasserIn)
Weitere Verfasser: Tong, Zhong-Hua, Chen, Jie-Jie, Li, Ling-Li, Yu, Han-Qing
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Ecotoxicology (London, England)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antimicrobial activity Copper nanoparticles Morphology Surface free energy Anti-Infective Agents Copper 789U1901C5 cuprous oxide mehr... T8BEA5064F cupric oxide V1XJQ704R4
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520 |a Cu/CuxO nanoparticles (NPs) with different morphologies have been synthesized with glucose as a reducing agent. The X-ray diffraction and Scanning electron microscopy imaging show that the Cu/CuxO NPs have fine crystalline peaks with homogeneous polyhedral, flower-like, and thumbtack-like morphologies. Their antimicrobial activities were evaluated on inactivation of Escherichia coli using a fluorescence-based live/dead staining method. Dissolution of copper ions from these NPs was determined. Results demonstrated a significant growth inhibition for these NPs with different morphologies, and the flower-like Cu/CuxO NPs were the most effective form, where more copper ions were dissolved into the culture media. Surface free energy calculations based on first-principle density functional theory show that different crystal facets of the copper NPs have diverse surface energy, indicating the highest reactivity of the flower-like NPs, which is consistent with the results from the dissolution study and antimicrobial activity test. Together, these results suggest that the difference between the surface free energy may be a cause for their morphology-dependent antimicrobial activity 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Antimicrobial activity 
650 4 |a Copper nanoparticles 
650 4 |a Morphology 
650 4 |a Surface free energy 
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650 7 |a 789U1901C5  |2 NLM 
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700 1 |a Tong, Zhong-Hua  |e verfasserin  |4 aut 
700 1 |a Chen, Jie-Jie  |e verfasserin  |4 aut 
700 1 |a Li, Ling-Li  |e verfasserin  |4 aut 
700 1 |a Yu, Han-Qing  |e verfasserin  |4 aut 
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