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231224s2015 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.5b02093
|2 doi
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|a pubmed24n0840.xml
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|a (DE-627)NLM252258118
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|a (NLM)26317405
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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|a Grubbs, Joe B
|c 3rd
|e verfasserin
|4 aut
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|a Degradable Polycaprolactone and Polylactide Homopolymer and Block Copolymer Brushes Prepared by Surface-Initiated Polymerization with Triazabicyclodecene and Zirconium Catalysts
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|c 2015
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 30.06.2016
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|a Date Revised 19.01.2021
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Surface-initiated ring-opening polymerization (SI-ROP) of polycaprolactone (PCL) and polylactide (PLA) polymer brushes with controlled degradation rates were prepared on oxide substrates. PCL brushes were polymerized from hydroxyl-terminated monolayers utilizing triazabicyclodecene (TBD) as the polymerization catalyst. A consistent brush thickness of 40 nm could be achieved with a reproducible unique crystalline morphology. The organocatalyzed PCL brushes were chain extended using lactide in the presence of zirconium n-butoxide to successfully grow PCL/PLA block copolymer (PCL-b-PLA) brushes with a final thickness of 55 nm. The degradation properties of "grafted from" PCL brush and the PCL-b-PLA brush were compared to "grafted to" PCL brushes, and we observed that the brush density plays a major role in degradation kinetics. Solutions of methanol/water at pH 14 were used to better solvate the brushes and increase the kinetics of degradation. This framework enables a control of degradation that allows for the precise removal of these coatings
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Azabicyclo Compounds
|2 NLM
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|a Polyesters
|2 NLM
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|a Polymers
|2 NLM
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|a triazabicyclodecene
|2 NLM
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|a polycaprolactone
|2 NLM
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|a 24980-41-4
|2 NLM
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|a poly(lactide)
|2 NLM
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|a 459TN2L5F5
|2 NLM
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|a Zirconium
|2 NLM
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|a C6V6S92N3C
|2 NLM
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|a Arnold, Rachelle M
|e verfasserin
|4 aut
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|a Roy, Anandi
|e verfasserin
|4 aut
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|a Durie, Karson
|e verfasserin
|4 aut
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|a Bilbrey, Jenna A
|e verfasserin
|4 aut
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|a Gao, Jing
|e verfasserin
|4 aut
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|a Locklin, Jason
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 31(2015), 37 vom: 22. Sept., Seite 10183-9
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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| 773 |
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|g volume:31
|g year:2015
|g number:37
|g day:22
|g month:09
|g pages:10183-9
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|u http://dx.doi.org/10.1021/acs.langmuir.5b02093
|3 Volltext
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