Discriminating a Single Nucleotide Difference for Enhanced miRNA Detection Using Tunable Graphene and Oligonucleotide Nanodevices

In this study we have reported our efforts to address some of the challenges in the detection of miRNAs using water-soluble graphene oxide and DNA nanoassemblies. Purposefully inserting mismatches at specific positions in our DNA (probe) strands shows increasing specificity against our target miRNA,...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 31(2015), 36 vom: 15. Sept., Seite 9943-52
1. Verfasser: Robertson, Neil M (VerfasserIn)
Weitere Verfasser: Hizir, Mustafa Salih, Balcioglu, Mustafa, Wang, Rui, Yavuz, Mustafa Selman, Yumak, Hasan, Ozturk, Birol, Sheng, Jia, Yigit, Mehmet V
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article MicroRNAs Oligonucleotides Graphite 7782-42-5