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20231224161002.0 |
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231224s2015 xx |||||o 00| ||eng c |
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7 |
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|a 10.1002/adma.201502767
|2 doi
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|a pubmed24n0836.xml
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|a (DE-627)NLM250976838
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|a (NLM)26184559
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|a DE-627
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|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Pakulska, Malgosia M
|e verfasserin
|4 aut
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1 |
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|a Hybrid Crosslinked Methylcellulose Hydrogel
|b A Predictable and Tunable Platform for Local Drug Delivery
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|c 2015
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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| 500 |
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|a Date Completed 06.06.2016
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|a Date Revised 30.09.2020
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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|a Design of experiment is used to develop a hybrid methylcellulose hydrogel that combines physical and chemical crosslinks, resulting in an injectable, in situ stiffening, and long-lasting material with predictable swelling and rheological properties. Chemical crosslinking is complete prior to injection, allowing for ease of use and storage. Controlled release of two relevant protein therapeutics and biocompatibility of the hydrogel are demonstrated
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a design of experiment
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|a drug delivery
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|a hydrogels
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|a rheology
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|a spinal cord injuries
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| 650 |
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|a Drug Carriers
|2 NLM
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|a Hydrogels
|2 NLM
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| 650 |
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|a Polylactic Acid-Polyglycolic Acid Copolymer
|2 NLM
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| 650 |
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|a 1SIA8062RS
|2 NLM
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| 650 |
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|a Polyglycolic Acid
|2 NLM
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|a 26009-03-0
|2 NLM
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| 650 |
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|a Lactic Acid
|2 NLM
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| 650 |
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|a 33X04XA5AT
|2 NLM
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| 650 |
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7 |
|a Methylcellulose
|2 NLM
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| 650 |
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|a 9004-67-5
|2 NLM
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| 700 |
1 |
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|a Vulic, Katarina
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Tam, Roger Y
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Shoichet, Molly S
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 27(2015), 34 vom: 09. Sept., Seite 5002-8
|w (DE-627)NLM098206397
|x 1521-4095
|7 nnns
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|g volume:27
|g year:2015
|g number:34
|g day:09
|g month:09
|g pages:5002-8
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|u http://dx.doi.org/10.1002/adma.201502767
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