Multifunctionality of Acidulated Serum Albumin on Inhibiting Zn²⁺-Mediated Amyloid β-Protein Fibrillogenesis and Cytotoxicity
Fibrillogenesis of amyloid β-proteins (Aβ) mediated by transition-metal ions such as Zn(2+) in neuronal cells plays a causative role in Alzheimer's disease. Hence, it is highly desired to design multifunctional agents capable of inhibiting Aβ aggregation and modulating metal-Aβ species. In this...
| Publié dans: | Langmuir : the ACS journal of surfaces and colloids. - 1985. - 31(2015), 26 vom: 07. Juli, Seite 7374-80 |
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| Auteur principal: | |
| Autres auteurs: | , , |
| Format: | Article en ligne |
| Langue: | English |
| Publié: |
2015
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| Accès à la collection: | Langmuir : the ACS journal of surfaces and colloids |
| Sujets: | Journal Article Research Support, Non-U.S. Gov't Amyloid beta-Peptides Peptide Fragments Serum Albumin amyloid beta-protein (1-42) Zinc J41CSQ7QDS |
| Accès en ligne |
Volltext |