Tunable nanostructured coating for the capture and selective release of viable circulating tumor cells

Tunable nanostructured coating for the capture and selective release of viable circulating tumor cells

© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Détails bibliographiques
Publié dans:Advanced materials (Deerfield Beach, Fla.). - 1998. - 27(2015), 9 vom: 04. März, Seite 1593-9
Auteur principal: Reátegui, Eduardo (Auteur)
Autres auteurs: Aceto, Nicola, Lim, Eugene J, Sullivan, James P, Jensen, Anne E, Zeinali, Mahnaz, Martel, Joseph M, Aranyosi, Alexander J, Li, Wei, Castleberry, Steven, Bardia, Aditya, Sequist, Lecia V, Haber, Daniel A, Maheswaran, Shyamala, Hammond, Paula T, Toner, Mehmet, Stott, Shannon L
Format: Article en ligne
Langue:English
Publié: 2015
Accès à la collection:Advanced materials (Deerfield Beach, Fla.)
Sujets:Evaluation Study Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't circulating tumor cells circulating tumor clusters microfluidics nanostructured coatings single cell sequencing Biocompatible Materials plus... Gelatin 9000-70-8
Description
Résumé:© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
A layer-by-layer gelatin nanocoating is presented for use as a tunable, dual response biomaterial for the capture and release of circulating tumor cells (CTCs) from cancer patient blood. The entire nanocoating can be dissolved from the surface of microfluidic devices through biologically compatible temperature shifts. Alternatively, individual CTCs can be released through locally applied mechanical stress
Description:Date Completed 06.11.2015
Date Revised 31.03.2022
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201404677