Tunable nanostructured coating for the capture and selective release of viable circulating tumor cells

Tunable nanostructured coating for the capture and selective release of viable circulating tumor cells

© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 27(2015), 9 vom: 04. März, Seite 1593-9
1. Verfasser: Reátegui, Eduardo (VerfasserIn)
Weitere Verfasser: Aceto, Nicola, Lim, Eugene J, Sullivan, James P, Jensen, Anne E, Zeinali, Mahnaz, Martel, Joseph M, Aranyosi, Alexander J, Li, Wei, Castleberry, Steven, Bardia, Aditya, Sequist, Lecia V, Haber, Daniel A, Maheswaran, Shyamala, Hammond, Paula T, Toner, Mehmet, Stott, Shannon L
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Evaluation Study Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't circulating tumor cells circulating tumor clusters microfluidics nanostructured coatings single cell sequencing Biocompatible Materials mehr... Gelatin 9000-70-8
Beschreibung
Zusammenfassung:© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
A layer-by-layer gelatin nanocoating is presented for use as a tunable, dual response biomaterial for the capture and release of circulating tumor cells (CTCs) from cancer patient blood. The entire nanocoating can be dissolved from the surface of microfluidic devices through biologically compatible temperature shifts. Alternatively, individual CTCs can be released through locally applied mechanical stress
Beschreibung:Date Completed 06.11.2015
Date Revised 31.03.2022
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201404677