Large-pore ultrasmall mesoporous organosilica nanoparticles micelle/precursor co-templating assembly and nuclear-targeted gene delivery

Large-pore ultrasmall mesoporous organosilica nanoparticles : micelle/precursor co-templating assembly and nuclear-targeted gene delivery

© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 27(2015), 2 vom: 14. Jan., Seite 215-22
1. Verfasser: Wu, Meiying (VerfasserIn)
Weitere Verfasser: Meng, Qingshuo, Chen, Yu, Du, Yanyan, Zhang, Lingxia, Li, Yaping, Zhang, Linlin, Shi, Jianlin
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't gene delivery large mesopores mesoporous organosilicas nuclear-targeted Biocompatible Materials Gene Products, tat Micelles Silicon Dioxide 7631-86-9
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520 |a A novel micelle/precursor co-templating assembly strategy is successfully developed to synthesize large-pore ultrasmall mesoporous organosilica nanoparticles (MONs). Furthermore, elaborately designed MONs with a cell-penetrating peptide (TAT) (MONs-PTAT) are constructed for highly efficient intranuclear gene delivery. They exhibit a high loading capacity, improved protection for the loaded gene, and enhanced transfection efficiencies of EGFP plasmid (pEGFP) 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a gene delivery 
650 4 |a large mesopores 
650 4 |a mesoporous organosilicas 
650 4 |a nuclear-targeted 
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650 7 |a Gene Products, tat  |2 NLM 
650 7 |a Micelles  |2 NLM 
650 7 |a Silicon Dioxide  |2 NLM 
650 7 |a 7631-86-9  |2 NLM 
700 1 |a Meng, Qingshuo  |e verfasserin  |4 aut 
700 1 |a Chen, Yu  |e verfasserin  |4 aut 
700 1 |a Du, Yanyan  |e verfasserin  |4 aut 
700 1 |a Zhang, Lingxia  |e verfasserin  |4 aut 
700 1 |a Li, Yaping  |e verfasserin  |4 aut 
700 1 |a Zhang, Linlin  |e verfasserin  |4 aut 
700 1 |a Shi, Jianlin  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Advanced materials (Deerfield Beach, Fla.)  |d 1998  |g 27(2015), 2 vom: 14. Jan., Seite 215-22  |w (DE-627)NLM098206397  |x 1521-4095  |7 nnns 
773 1 8 |g volume:27  |g year:2015  |g number:2  |g day:14  |g month:01  |g pages:215-22 
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