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231224s2014 xx |||||o 00| ||eng c |
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|a 10.1002/adma.201401931
|2 doi
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|a pubmed25n0800.xml
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|e rakwb
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|a eng
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|a Croissant, Jonas
|e verfasserin
|4 aut
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|a Biodegradable ethylene-bis(propyl)disulfide-based periodic mesoporous organosilica nanorods and nanospheres for efficient in-vitro drug delivery
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|c 2014
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|a Date Completed 08.06.2015
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|a Date Revised 30.09.2020
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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|a Periodic mesoporous organosilica nanorods and nanospheres are synthesized from 1,4-bis(triethoxysilyl)ethylene and bis(3-ethoxysilylpropyl)disulfide. The nanosystems present the long-range order of the hexagonal nanostructure. They are degraded in simulated physiological conditions. The loading and release of doxorubicin with these nanosystems are both pH dependent. These nanoparticles are endocytosed by breast cancer cells and are very efficient for doxorubicin delivery in these cells
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a biodegradable
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|a cancer
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|a disulfide
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|a drug delivery
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|a nanoparticles
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|a periodic mesoporous organosilica
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|a Antibiotics, Antineoplastic
|2 NLM
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|a Disulfides
|2 NLM
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|a Drug Carriers
|2 NLM
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|a Ethylenes
|2 NLM
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|a Silicon Dioxide
|2 NLM
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|a 7631-86-9
|2 NLM
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|a Doxorubicin
|2 NLM
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|a 80168379AG
|2 NLM
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|a ethylene
|2 NLM
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|a 91GW059KN7
|2 NLM
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|a Cattoën, Xavier
|e verfasserin
|4 aut
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|a Man, Michel Wong Chi
|e verfasserin
|4 aut
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|a Gallud, Audrey
|e verfasserin
|4 aut
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|a Raehm, Laurence
|e verfasserin
|4 aut
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|a Trens, Philippe
|e verfasserin
|4 aut
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|a Maynadier, Marie
|e verfasserin
|4 aut
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|a Durand, Jean-Olivier
|e verfasserin
|4 aut
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|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 26(2014), 35 vom: 17. Sept., Seite 6174-80
|w (DE-627)NLM098206397
|x 1521-4095
|7 nnns
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|g volume:26
|g year:2014
|g number:35
|g day:17
|g month:09
|g pages:6174-80
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|u http://dx.doi.org/10.1002/adma.201401931
|3 Volltext
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