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231224s2014 xx |||||o 00| ||eng c |
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|a 10.1107/S1600577514010388
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|a eng
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|a Vartiainen, Ismo
|e verfasserin
|4 aut
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|a Towards tender X-rays with Zernike phase-contrast imaging of biological samples at 50 nm resolution
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|c 2014
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|a Text
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|a ƒaComputermedien
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|a Date Completed 30.09.2015
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|a Date Revised 28.06.2014
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a X-ray microscopy is a commonly used method especially in material science application, where the large penetration depth of X-rays is necessary for three-dimensional structural studies of thick specimens with high-Z elements. In this paper it is shown that full-field X-ray microscopy at 6.2 keV can be utilized for imaging of biological specimens with high resolution. A full-field Zernike phase-contrast microscope based on diffractive optics is used to study lipid droplet formation in hepatoma cells. It is shown that the contrast of the images is comparable with that of electron microscopy, and even better contrast at tender X-ray energies between 2.5 keV and 4 keV is expected
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a X-ray microscopy
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|a Zernike phase contrast
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|a biological samples
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|a Warmer, Martin
|e verfasserin
|4 aut
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|a Goeries, Dennis
|e verfasserin
|4 aut
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|a Herker, Eva
|e verfasserin
|4 aut
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|a Reimer, Rudolph
|e verfasserin
|4 aut
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|a David, Christian
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|a Meents, Alke
|e verfasserin
|4 aut
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|i Enthalten in
|t Journal of synchrotron radiation
|d 1994
|g 21(2014), Pt 4 vom: 21. Juli, Seite 790-4
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|x 1600-5775
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|g volume:21
|g year:2014
|g number:Pt 4
|g day:21
|g month:07
|g pages:790-4
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|u http://dx.doi.org/10.1107/S1600577514010388
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