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231224s2014 xx |||||o 00| ||eng c |
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|a 10.1111/vcp.12139
|2 doi
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|a pubmed24n0791.xml
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|a (DE-627)NLM237352575
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|a (NLM)24731227
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|a DE-627
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|e rakwb
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|a eng
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|a Tefft, Karen M
|e verfasserin
|4 aut
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|a Association between excess body weight and urine protein concentration in healthy dogs
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|c 2014
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 16.04.2015
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|a Date Revised 20.10.2016
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2014 American Society for Veterinary Clinical Pathology and European Society for Veterinary Clinical Pathology.
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|a BACKGROUND: Markedly overweight people can develop progressive proteinuria and kidney failure secondary to obesity-related glomerulopathy (ORG). Glomerular lesions in dogs with experimentally induced obesity are similar to those in people with ORG
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|a OBJECTIVES: The aim of this study was to evaluate if urine protein and albumin excretion is greater in overweight and obese dogs than in dogs of ideal body condition
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|a METHODS: Client-owned dogs were screened for underlying health conditions. These dogs were assigned a body condition score (BCS) using a 9-point scoring system. Dogs with a BCS of ≥ 6 were classified as being overweight/obese, and dogs with a BCS of 4 or 5 were classified as being of ideal body weight. The urine protein:creatinine ratio (UPC) and urine albumin:creatinine ratio (UAC) were then determined, and compared between 20 overweight/obese dogs and 22 ideal body weight control dogs
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|a RESULTS: Median UPC (0.04 [range, 0.01-0.14; interquartile range, 0.07]) and UAC (0.41 [0-10.39; 3.21]) of overweight/obese dogs were not significantly different from median UPC (0.04 [0.01-0.32; 0.07]) and UAC (0.18 [0-7.04; 1.75]) in ideal body weight dogs
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|a CONCLUSIONS: Clinicopathologic abnormalities consistent with ORG were absent from overweight/obese dogs in this study
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Body condition score
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|a canine
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|a microalbuminuria
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|a obesity-related glomerulopathy
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|a urine protein:creatinine ratio
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|a Creatinine
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|a Shaw, Darcy H
|e verfasserin
|4 aut
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|a Ihle, Sherri L
|e verfasserin
|4 aut
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|a Burton, Shelley A
|e verfasserin
|4 aut
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|a Pack, LeeAnn
|e verfasserin
|4 aut
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|i Enthalten in
|t Veterinary clinical pathology
|d 1975
|g 43(2014), 2 vom: 14. Juni, Seite 255-60
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|x 1939-165X
|7 nnns
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|g volume:43
|g year:2014
|g number:2
|g day:14
|g month:06
|g pages:255-60
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|u http://dx.doi.org/10.1111/vcp.12139
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