Association between excess body weight and urine protein concentration in healthy dogs

© 2014 American Society for Veterinary Clinical Pathology and European Society for Veterinary Clinical Pathology.

Bibliographische Detailangaben
Veröffentlicht in:Veterinary clinical pathology. - 1975. - 43(2014), 2 vom: 14. Juni, Seite 255-60
1. Verfasser: Tefft, Karen M (VerfasserIn)
Weitere Verfasser: Shaw, Darcy H, Ihle, Sherri L, Burton, Shelley A, Pack, LeeAnn
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Veterinary clinical pathology
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Body condition score canine microalbuminuria obesity-related glomerulopathy urine protein:creatinine ratio Creatinine AYI8EX34EU
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245 1 0 |a Association between excess body weight and urine protein concentration in healthy dogs 
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500 |a Date Completed 16.04.2015 
500 |a Date Revised 20.10.2016 
500 |a published: Print-Electronic 
500 |a Citation Status MEDLINE 
520 |a © 2014 American Society for Veterinary Clinical Pathology and European Society for Veterinary Clinical Pathology. 
520 |a BACKGROUND: Markedly overweight people can develop progressive proteinuria and kidney failure secondary to obesity-related glomerulopathy (ORG). Glomerular lesions in dogs with experimentally induced obesity are similar to those in people with ORG 
520 |a OBJECTIVES: The aim of this study was to evaluate if urine protein and albumin excretion is greater in overweight and obese dogs than in dogs of ideal body condition 
520 |a METHODS: Client-owned dogs were screened for underlying health conditions. These dogs were assigned a body condition score (BCS) using a 9-point scoring system. Dogs with a BCS of ≥ 6 were classified as being overweight/obese, and dogs with a BCS of 4 or 5 were classified as being of ideal body weight. The urine protein:creatinine ratio (UPC) and urine albumin:creatinine ratio (UAC) were then determined, and compared between 20 overweight/obese dogs and 22 ideal body weight control dogs 
520 |a RESULTS: Median UPC (0.04 [range, 0.01-0.14; interquartile range, 0.07]) and UAC (0.41 [0-10.39; 3.21]) of overweight/obese dogs were not significantly different from median UPC (0.04 [0.01-0.32; 0.07]) and UAC (0.18 [0-7.04; 1.75]) in ideal body weight dogs 
520 |a CONCLUSIONS: Clinicopathologic abnormalities consistent with ORG were absent from overweight/obese dogs in this study 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Body condition score 
650 4 |a canine 
650 4 |a microalbuminuria 
650 4 |a obesity-related glomerulopathy 
650 4 |a urine protein:creatinine ratio 
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700 1 |a Shaw, Darcy H  |e verfasserin  |4 aut 
700 1 |a Ihle, Sherri L  |e verfasserin  |4 aut 
700 1 |a Burton, Shelley A  |e verfasserin  |4 aut 
700 1 |a Pack, LeeAnn  |e verfasserin  |4 aut 
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773 1 8 |g volume:43  |g year:2014  |g number:2  |g day:14  |g month:06  |g pages:255-60 
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