Differential flow rate of commercially available triamcinolone with and without preservative through small-gauge needles

Copyright 2014, SLACK Incorporated.

Bibliographische Detailangaben
Veröffentlicht in:Ophthalmic surgery, lasers & imaging retina. - 2013. - 45(2014), 1 vom: 17. Jan., Seite 54-7
1. Verfasser: Cabrera, Mariana (VerfasserIn)
Weitere Verfasser: Gonzalez, Alex, Albini, Thomas A, Rowaan, Cornelis, Aguilar, Mariela, Lee, William, Fortun, Jorge A, Moshfeghi, Andrew A, Flynn, Harry W Jr, Parel, Jean-Marie A
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Ophthalmic surgery, lasers & imaging retina
Schlagworte:Comparative Study Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Glucocorticoids Ophthalmic Solutions Preservatives, Pharmaceutical Triamcinolone Acetonide F446C597KA Benzyl Alcohol LKG8494WBH
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245 1 0 |a Differential flow rate of commercially available triamcinolone with and without preservative through small-gauge needles 
264 1 |c 2014 
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500 |a Date Revised 25.11.2016 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a Copyright 2014, SLACK Incorporated. 
520 |a OBJECTIVE: To compare the flow rate through different gauge needles of triamcinolone acetonide with benzyl alcohol (TABA) versus preservative-free triamcinolone acetonide injectable suspension (TAIS) 
520 |a MATERIALS AND METHODS: Experimental injections of 1 mL of TABA or TAIS were performed through a 27-, 30-, or 32-gauge needle. A piezoelectric pressure transducer connected to a personal computer was placed between the syringe and needle to record the force-time relationship and assess the flow rate (mL/s). Measurements were performed in triplicate 
520 |a RESULTS: Flow rates were similar between preparations using a 27-gauge needle. Using a 30-gauge needle, the flow rate was 0.058 mL/s for TABA and 0.178 mL/s for TAIS. Using a 32-gauge needle, no flow was sustained by TABA, whereas the flow rate of TAIS was 0.114 mL/s (P < .05) 
520 |a CONCLUSION: TAIS can be injected through a 32-gauge needle without the risk of obstruction. Occlusions were seen with TABA using the 30- and 32-gauge needles 
650 4 |a Comparative Study 
650 4 |a Journal Article 
650 4 |a Research Support, N.I.H., Extramural 
650 4 |a Research Support, Non-U.S. Gov't 
650 7 |a Glucocorticoids  |2 NLM 
650 7 |a Ophthalmic Solutions  |2 NLM 
650 7 |a Preservatives, Pharmaceutical  |2 NLM 
650 7 |a Triamcinolone Acetonide  |2 NLM 
650 7 |a F446C597KA  |2 NLM 
650 7 |a Benzyl Alcohol  |2 NLM 
650 7 |a LKG8494WBH  |2 NLM 
700 1 |a Gonzalez, Alex  |e verfasserin  |4 aut 
700 1 |a Albini, Thomas A  |e verfasserin  |4 aut 
700 1 |a Rowaan, Cornelis  |e verfasserin  |4 aut 
700 1 |a Aguilar, Mariela  |e verfasserin  |4 aut 
700 1 |a Lee, William  |e verfasserin  |4 aut 
700 1 |a Fortun, Jorge A  |e verfasserin  |4 aut 
700 1 |a Moshfeghi, Andrew A  |e verfasserin  |4 aut 
700 1 |a Flynn, Harry W  |c Jr  |e verfasserin  |4 aut 
700 1 |a Parel, Jean-Marie A  |e verfasserin  |4 aut 
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773 1 8 |g volume:45  |g year:2014  |g number:1  |g day:17  |g month:01  |g pages:54-7 
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