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231224s2014 xx |||||o 00| ||eng c |
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|a 10.3928/23258160-20131220-08
|2 doi
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|a pubmed24n0780.xml
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|a (DE-627)NLM234184590
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|a (NLM)24392913
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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|a Cabrera, Mariana
|e verfasserin
|4 aut
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|a Differential flow rate of commercially available triamcinolone with and without preservative through small-gauge needles
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|c 2014
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 17.07.2014
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|a Date Revised 25.11.2016
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|a published: Print
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|a Citation Status MEDLINE
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|a Copyright 2014, SLACK Incorporated.
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|a OBJECTIVE: To compare the flow rate through different gauge needles of triamcinolone acetonide with benzyl alcohol (TABA) versus preservative-free triamcinolone acetonide injectable suspension (TAIS)
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|a MATERIALS AND METHODS: Experimental injections of 1 mL of TABA or TAIS were performed through a 27-, 30-, or 32-gauge needle. A piezoelectric pressure transducer connected to a personal computer was placed between the syringe and needle to record the force-time relationship and assess the flow rate (mL/s). Measurements were performed in triplicate
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|a RESULTS: Flow rates were similar between preparations using a 27-gauge needle. Using a 30-gauge needle, the flow rate was 0.058 mL/s for TABA and 0.178 mL/s for TAIS. Using a 32-gauge needle, no flow was sustained by TABA, whereas the flow rate of TAIS was 0.114 mL/s (P < .05)
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|a CONCLUSION: TAIS can be injected through a 32-gauge needle without the risk of obstruction. Occlusions were seen with TABA using the 30- and 32-gauge needles
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|a Comparative Study
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|a Journal Article
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|a Research Support, N.I.H., Extramural
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|a Research Support, Non-U.S. Gov't
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|a Glucocorticoids
|2 NLM
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|a Ophthalmic Solutions
|2 NLM
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|a Preservatives, Pharmaceutical
|2 NLM
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|a Triamcinolone Acetonide
|2 NLM
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|a F446C597KA
|2 NLM
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|a Benzyl Alcohol
|2 NLM
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|a LKG8494WBH
|2 NLM
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1 |
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|a Gonzalez, Alex
|e verfasserin
|4 aut
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1 |
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|a Albini, Thomas A
|e verfasserin
|4 aut
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1 |
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|a Rowaan, Cornelis
|e verfasserin
|4 aut
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1 |
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|a Aguilar, Mariela
|e verfasserin
|4 aut
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1 |
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|a Lee, William
|e verfasserin
|4 aut
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1 |
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|a Fortun, Jorge A
|e verfasserin
|4 aut
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1 |
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|a Moshfeghi, Andrew A
|e verfasserin
|4 aut
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1 |
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|a Flynn, Harry W
|c Jr
|e verfasserin
|4 aut
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|a Parel, Jean-Marie A
|e verfasserin
|4 aut
|
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0 |
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|i Enthalten in
|t Ophthalmic surgery, lasers & imaging retina
|d 2013
|g 45(2014), 1 vom: 17. Jan., Seite 54-7
|w (DE-627)NLM224956647
|x 2325-8179
|7 nnns
|
773 |
1 |
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|g volume:45
|g year:2014
|g number:1
|g day:17
|g month:01
|g pages:54-7
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|u http://dx.doi.org/10.3928/23258160-20131220-08
|3 Volltext
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|d 45
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