Differential flow rate of commercially available triamcinolone with and without preservative through small-gauge needles
Copyright 2014, SLACK Incorporated.
| Veröffentlicht in: | Ophthalmic surgery, lasers & imaging retina. - 2013. - 45(2014), 1 vom: 17. Jan., Seite 54-7 |
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| 1. Verfasser: | |
| Weitere Verfasser: | , , , , , , , , |
| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2014
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| Zugriff auf das übergeordnete Werk: | Ophthalmic surgery, lasers & imaging retina |
| Schlagworte: | Comparative Study Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Glucocorticoids Ophthalmic Solutions Preservatives, Pharmaceutical Triamcinolone Acetonide F446C597KA Benzyl Alcohol |
| Zusammenfassung: | Copyright 2014, SLACK Incorporated. OBJECTIVE: To compare the flow rate through different gauge needles of triamcinolone acetonide with benzyl alcohol (TABA) versus preservative-free triamcinolone acetonide injectable suspension (TAIS) MATERIALS AND METHODS: Experimental injections of 1 mL of TABA or TAIS were performed through a 27-, 30-, or 32-gauge needle. A piezoelectric pressure transducer connected to a personal computer was placed between the syringe and needle to record the force-time relationship and assess the flow rate (mL/s). Measurements were performed in triplicate RESULTS: Flow rates were similar between preparations using a 27-gauge needle. Using a 30-gauge needle, the flow rate was 0.058 mL/s for TABA and 0.178 mL/s for TAIS. Using a 32-gauge needle, no flow was sustained by TABA, whereas the flow rate of TAIS was 0.114 mL/s (P < .05) CONCLUSION: TAIS can be injected through a 32-gauge needle without the risk of obstruction. Occlusions were seen with TABA using the 30- and 32-gauge needles |
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| Beschreibung: | Date Completed 17.07.2014 Date Revised 25.11.2016 published: Print Citation Status MEDLINE |
| ISSN: | 2325-8179 |
| DOI: | 10.3928/23258160-20131220-08 |