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231224s2014 xx |||||o 00| ||eng c |
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7 |
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|a 10.1002/adma.201304607
|2 doi
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|a pubmed24n1338.xml
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|a eng
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| 100 |
1 |
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|a Tseng, Peter
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Substrates with patterned extracellular matrix and subcellular stiffness gradients reveal local biomechanical responses
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|c 2014
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| 336 |
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|a Date Completed 03.12.2014
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|a Date Revised 21.03.2024
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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|a A substrate fabrication process is developed to pattern both the extracellular matrix (ECM) and rigidity at sub-cellular spatial resolution. When growing cells on these substrates, it is found that cells respond locally in their cytoskeleton assembly. The presented method allows unique insight into the biological interpretation of mechanical signals, whereas photolithography-based fabrication is amenable to integration with complex microfabricated substructures
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|a Journal Article
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|a Research Support, N.I.H., Extramural
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|a BioMEMS
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|a biomechanics
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|a cell control
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|a mechanotransduction
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|a stress fibers
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|a Actins
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|a Culture Media
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|a Dimethylpolysiloxanes
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| 650 |
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| 700 |
1 |
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|a Di Carlo, Dino
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 26(2014), 8 vom: 26. Feb., Seite 1242-7
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|u http://dx.doi.org/10.1002/adma.201304607
|3 Volltext
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