Establishment of a derivatization method to quantify thiol function in sulfur-containing plasma polymer films
Thiol-supported surfaces draw more and more interest in numerous fields of applications from biotechnology to catalysis. Among the various strategies to generate such surfaces, the plasma polymerization of a thiol-containing molecule appears to be one of the ideal candidates. Nevertheless, consideri...
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1992. - 29(2013), 43 vom: 29. Okt., Seite 13183-9 |
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| 1. Verfasser: | |
| Weitere Verfasser: | , , , , |
| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2013
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids |
| Schlagworte: | Journal Article Research Support, Non-U.S. Gov't Polymers Sulfhydryl Compounds Sulfur 70FD1KFU70 Ethylmaleimide O3C74ACM9V |
| Zusammenfassung: | Thiol-supported surfaces draw more and more interest in numerous fields of applications from biotechnology to catalysis. Among the various strategies to generate such surfaces, the plasma polymerization of a thiol-containing molecule appears to be one of the ideal candidates. Nevertheless, considering such an approach, a careful characterization of the material surface chemistry is necessary. In this work, an original chemical derivatization method aiming to quantitatively probe the -SH functions in plasma polymers was established using N-ethylmaleimide as a labeling molecule. The method was qualitatively and quantitatively validated on self-assembled monolayers of 3-mercaptopropyltrimethoxysilane exhibiting a -SH-terminated group used as "model" surface. For a quantitative determination of the -SH content in propanethiol plasma polymers, the kinetics of the reaction was investigated. The latter is described as a two-step mechanism, namely a fast surface reaction followed by a diffusion-limited one. The density of -SH groups deduced from the derivatization method (~4%) is in good agreement with typical values measured in some other plasma polymer families. The whole set of our data opens up new possibilities for optimizing the -SH content in thiol-based plasma polymer films |
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| Beschreibung: | Date Completed 21.05.2014 Date Revised 29.10.2013 published: Print-Electronic Citation Status MEDLINE |
| ISSN: | 1520-5827 |
| DOI: | 10.1021/la402891t |