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231224s2013 xx |||||o 00| ||eng c |
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7 |
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|a 10.1002/adma.201300526
|2 doi
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|a pubmed24n0765.xml
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|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Moga, Katherine A
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Rapidly-dissolvable microneedle patches via a highly scalable and reproducible soft lithography approach
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| 264 |
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|c 2013
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| 336 |
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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| 500 |
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|a Date Completed 21.04.2014
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|a Date Revised 21.10.2021
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|a published: Print-Electronic
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|a Citation Status PubMed-not-MEDLINE
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|a © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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|a Microneedle devices for transdermal drug delivery have recently become an attractive method to overcome the diffusion-limiting epidermis and effectively transport therapeutics to the body. Here, we demonstrate the fabrication of highly reproducible and completely dissolvable polymer microneedles on flexible water-soluble substrates. These biocompatible microneedles (made by using a soft lithography process known as PRINT) showed efficacy in piercing both murine and human skin samples and delivering a fluorescent drug surrogate to the tissue
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a PRINT
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|a drug delivery
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4 |
|a microneedles
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| 650 |
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4 |
|a microprojections
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| 650 |
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4 |
|a soft lithography
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| 700 |
1 |
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|a Bickford, Lissett R
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Geil, Robert D
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Dunn, Stuart S
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Pandya, Ashish A
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wang, Yapei
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Fain, John H
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Archuleta, Christine F
|e verfasserin
|4 aut
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| 700 |
1 |
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|a O'Neill, Adrian T
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Desimone, Joseph M
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 25(2013), 36 vom: 25. Sept., Seite 5060-6
|w (DE-627)NLM098206397
|x 1521-4095
|7 nnns
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| 773 |
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|g volume:25
|g year:2013
|g number:36
|g day:25
|g month:09
|g pages:5060-6
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|u http://dx.doi.org/10.1002/adma.201300526
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