Rapidly-dissolvable microneedle patches via a highly scalable and reproducible soft lithography approach

Rapidly-dissolvable microneedle patches via a highly scalable and reproducible soft lithography approach

© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 25(2013), 36 vom: 25. Sept., Seite 5060-6
1. Verfasser: Moga, Katherine A (VerfasserIn)
Weitere Verfasser: Bickford, Lissett R, Geil, Robert D, Dunn, Stuart S, Pandya, Ashish A, Wang, Yapei, Fain, John H, Archuleta, Christine F, O'Neill, Adrian T, Desimone, Joseph M
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't PRINT drug delivery microneedles microprojections soft lithography
Beschreibung
Zusammenfassung:© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Microneedle devices for transdermal drug delivery have recently become an attractive method to overcome the diffusion-limiting epidermis and effectively transport therapeutics to the body. Here, we demonstrate the fabrication of highly reproducible and completely dissolvable polymer microneedles on flexible water-soluble substrates. These biocompatible microneedles (made by using a soft lithography process known as PRINT) showed efficacy in piercing both murine and human skin samples and delivering a fluorescent drug surrogate to the tissue
Beschreibung:Date Completed 21.04.2014
Date Revised 21.10.2021
published: Print-Electronic
Citation Status PubMed-not-MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201300526