Study of wild-type α-synuclein binding and orientation on gold nanoparticles

The disruption of α-synuclein (α-syn) homeostasis in neurons is a potential cause of Parkinson's disease, which is manifested pathologically by the appearance of α-syn aggregates, or Lewy bodies. Treatments for neurological diseases are extremely limited. To study the potential use of gold nano...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 29(2013), 14 vom: 09. Apr., Seite 4603-15
1. Verfasser: Yang, Jie An (VerfasserIn)
Weitere Verfasser: Johnson, Brittany J, Wu, Sway, Woods, Wendy S, George, Julia M, Murphy, Catherine J
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, U.S. Gov't, Non-P.H.S. alpha-Synuclein Gold 7440-57-5 Trypsin EC 3.4.21.4