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231224s2013 xx |||||o 00| ||eng c |
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|a 10.1002/adma.201202881
|2 doi
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|a pubmed24n1435.xml
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|a eng
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| 100 |
1 |
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|a Heller, Daniel A
|e verfasserin
|4 aut
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|a Modular 'click-in-emulsion' bone-targeted nanogels
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|c 2013
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|a Date Completed 03.09.2013
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|a Date Revised 10.06.2024
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|a published: Print-Electronic
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|a Citation Status PubMed-not-MEDLINE
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|a Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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|a A new class of nanogel demonstrates modular biodistribution and affinity for bone. Nanogels, ∼70 nm in diameter and synthesized via an astoichiometric click-chemistry in-emulsion method, controllably display residual, free clickable functional groups. Functionalization with a bisphosphonate ligand results in significant binding to bone on the inner walls of marrow cavities, liver avoidance, and anti-osteoporotic effects
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|a Journal Article
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|a Research Support, N.I.H., Extramural
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|a Research Support, Non-U.S. Gov't
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|a Levi, Yair
|e verfasserin
|4 aut
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| 700 |
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|a Pelet, Jeisa M
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Doloff, Joshua C
|e verfasserin
|4 aut
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| 700 |
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|a Wallas, Jasmine
|e verfasserin
|4 aut
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| 700 |
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|a Pratt, George W
|e verfasserin
|4 aut
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|a Jiang, Shan
|e verfasserin
|4 aut
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|a Sahay, Gaurav
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| 700 |
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|a Schroeder, Avi
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|4 aut
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|a Schroeder, Josh E
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|4 aut
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|a Chyan, Yieu
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|4 aut
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| 700 |
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|a Zurenko, Christopher
|e verfasserin
|4 aut
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| 700 |
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|a Querbes, William
|e verfasserin
|4 aut
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| 700 |
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|a Manzano, Miguel
|e verfasserin
|4 aut
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| 700 |
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|a Kohane, Daniel S
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| 700 |
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|a Langer, Robert
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|a Anderson, Daniel G
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|t Advanced materials (Deerfield Beach, Fla.)
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|g 25(2013), 10 vom: 13. März, Seite 1449-54
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