Effects of urea on selectivity and protein-ligand interactions in multimodal cation exchange chromatography
Nuclear magnetic resonance (NMR) and molecular dynamics (MD) simulations were employed in concert with chromatography to provide insight into the effect of urea on protein-ligand interactions in multimodal (MM) chromatography. Chromatographic experiments with a protein library in ion exchange (IEX)...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1992. - 29(2013), 1 vom: 08. Jan., Seite 158-67
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| 1. Verfasser: |
Holstein, Melissa A
(VerfasserIn) |
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| Weitere Verfasser: |
Parimal, Siddharth,
McCallum, Scott A,
Cramer, Steven M |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2013
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Ligands
Proteins
Ubiquitin
Urea
8W8T17847W |
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