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231224s2012 xx |||||o 00| ||eng c |
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|a 10.1002/adma.201202961
|2 doi
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|a pubmed24n0736.xml
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|a eng
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|a Myung, Sung
|e verfasserin
|4 aut
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|a Label-free polypeptide-based enzyme detection using a graphene-nanoparticle hybrid sensor
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|c 2012
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|a Date Completed 01.05.2013
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|a Date Revised 21.10.2021
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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|a A graphene-nanoparticle (NP) hybrid biosensor that utilizes an electrical hysteresis change to detect the enzymatic activity and concentration of Carboxypeptidase B was developed. The results indicate that the novel graphene-NP hybrid biosensor, utilizing electrical hysteresis, has the ability to detect concentrations of targeted enzyme on the micromolar scale. Furthermore, to the knowledge of the authors, this is the first demonstration of a graphene-based biosensor that utilizes a hysteresis change resulting from metallic NPs assembled on a graphene surface
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|a Journal Article
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|a Research Support, N.I.H., Extramural
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|a Research Support, Non-U.S. Gov't
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|a Peptides
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|a 7782-42-5
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|a Carboxypeptidase B
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|a EC 3.4.17.2
|2 NLM
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|a Yin, Perry T
|e verfasserin
|4 aut
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|a Kim, Cheoljin
|e verfasserin
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|a Park, Jaesung
|e verfasserin
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|a Solanki, Aniruddh
|e verfasserin
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|a Reyes, Pavel Ivanoff
|e verfasserin
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|a Lu, Yicheng
|e verfasserin
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|a Kim, Kwang S
|e verfasserin
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|a Lee, Ki-Bum
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 24(2012), 45 vom: 27. Nov., Seite 6081-7
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