Label-free polypeptide-based enzyme detection using a graphene-nanoparticle hybrid sensor

Label-free polypeptide-based enzyme detection using a graphene-nanoparticle hybrid sensor

Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 24(2012), 45 vom: 27. Nov., Seite 6081-7
1. Verfasser: Myung, Sung (VerfasserIn)
Weitere Verfasser: Yin, Perry T, Kim, Cheoljin, Park, Jaesung, Solanki, Aniruddh, Reyes, Pavel Ivanoff, Lu, Yicheng, Kim, Kwang S, Lee, Ki-Bum
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Peptides Graphite 7782-42-5 Carboxypeptidase B EC 3.4.17.2
Beschreibung
Zusammenfassung:Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
A graphene-nanoparticle (NP) hybrid biosensor that utilizes an electrical hysteresis change to detect the enzymatic activity and concentration of Carboxypeptidase B was developed. The results indicate that the novel graphene-NP hybrid biosensor, utilizing electrical hysteresis, has the ability to detect concentrations of targeted enzyme on the micromolar scale. Furthermore, to the knowledge of the authors, this is the first demonstration of a graphene-based biosensor that utilizes a hysteresis change resulting from metallic NPs assembled on a graphene surface
Beschreibung:Date Completed 01.05.2013
Date Revised 21.10.2021
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201202961