Inhibition of cellular efflux pumps involved in multi xenobiotic resistance (MXR) in echinoid larvae as a possible mode of action for increased ecotoxicological risk of mixtures

In marine organisms the multi xenobiotic resistance (MXR) mechanism via e.g. P-glycoprotein (P-gp) and multidrug resistance-associated protein (MRP) is an important first line of defense against contaminants by pumping contaminants out of the cells. If compounds would impair the MXR mechanism, this...

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Bibliographische Detailangaben

Veröffentlicht in:	Ecotoxicology (London, England). - 1992. - 21(2012), 8 vom: 07. Nov., Seite 2276-87
1. Verfasser:	Anselmo, Henrique M R (VerfasserIn)
Weitere Verfasser:	van den Berg, Johannes H J, Rietjens, Ivonne M C M, Murk, Albertinka J
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2012
Zugriff auf das übergeordnete Werk:	Ecotoxicology (London, England)
Schlagworte:	Evaluation Study Journal Article Research Support, Non-U.S. Gov't Fluoresceins Xenobiotics fluorexon V0YM2B16TS