Modeling negative cooperativity in streptavidin adsorption onto biotinylated microtubules

The nanoscale architecture of binding sites can result in complex binding kinetics. Here, the adsorption of streptavidin and neutravidin to biotinylated microtubules is found to exhibit negative cooperativity due to electrostatic interactions and steric hindrance. This behavior is modeled by a newly...

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Veröffentlicht in:	Langmuir : the ACS journal of surfaces and colloids. - 1999. - 28(2012), 29 vom: 24. Juli, Seite 10635-9
1. Verfasser:	He, Siheng (VerfasserIn)
Weitere Verfasser:	Lam, Amy T, Jeune-Smith, Yolaine, Hess, Henry
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2012
Zugriff auf das übergeordnete Werk:	Langmuir : the ACS journal of surfaces and colloids
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. neutravidin Avidin 1405-69-2 Biotin 6SO6U10H04 Streptavidin 9013-20-1