Identification of nuclear localization signal in ASYMMETRIC LEAVES2-LIKE18/LATERAL ORGAN BOUNDARIES DOMAIN16 (ASL18/LBD16) from Arabidopsis

Copyright © 2012 Elsevier GmbH. All rights reserved.

Détails bibliographiques
Publié dans:Journal of plant physiology. - 1979. - 169(2012), 12 vom: 15. Aug., Seite 1221-6
Auteur principal: Kim, Min-Jung (Auteur)
Autres auteurs: Kim, Jungmook
Format: Article en ligne
Langue:English
Publié: 2012
Accès à la collection:Journal of plant physiology
Sujets:Journal Article Research Support, Non-U.S. Gov't Arabidopsis Proteins LBD18 protein, Arabidopsis Nuclear Localization Signals Transcription Factors
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245 1 0 |a Identification of nuclear localization signal in ASYMMETRIC LEAVES2-LIKE18/LATERAL ORGAN BOUNDARIES DOMAIN16 (ASL18/LBD16) from Arabidopsis 
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520 |a The ASYMMETRIC LEAVES2-LIKE/LATERAL ORGAN BOUNDARIES DOMAIN (ASL/LBD) gene family encodes proteins harboring a conserved plant-specific LOB domain. The LOB domain contains a four-Cys motif, a Gly-Ala-Ser (GAS) block, and a Leu-zipper-like coiled-coil motif. The ASL/LBD proteins are a unique class of transcription factors that play roles in lateral organ development of plants. Although the ASL/LBD proteins are localized in the nucleus, no consensus sequence for the nuclear localization of the ASL/LBD proteins could be found. In the present study, we determined the motifs responsible for the nuclear localization of ASL18/LBD16 by using protoplast transfection assays with a variety N- or C-terminal deletion polypeptide fragments and the polypeptides harboring changes in basic amino acids that are fused to enhanced green fluorescent protein. The results demonstrated that ASL18/LBD16 harbors two distinct domains comprising an atypical nuclear localization signal (NLS) with basic amino acid residues in the coiled-coil motif and a monopartite-like NLS in the C-terminal region for nuclear targeting 
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650 7 |a Arabidopsis Proteins  |2 NLM 
650 7 |a LBD18 protein, Arabidopsis  |2 NLM 
650 7 |a Nuclear Localization Signals  |2 NLM 
650 7 |a Transcription Factors  |2 NLM 
700 1 |a Kim, Jungmook  |e verfasserin  |4 aut 
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