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231224s2012 xx |||||o 00| ||eng c |
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|a 10.1002/adma.201200412
|2 doi
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|a eng
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|a Wu, Li
|e verfasserin
|4 aut
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|a Label-free ultrasensitive detection of human telomerase activity using porphyrin-functionalized graphene and electrochemiluminescence technique
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|c 2012
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|a Text
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|a ƒaComputermedien
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|a Date Completed 04.09.2012
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|a Date Revised 30.09.2020
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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|a Using porphyrin-functionalized graphene, we construct a PCR-free, low-cost, rapid, and electrochemiluminenscence (ECL) assay for detection of telomerase activity that has been demonstrated in six different cell lines and can be used as initial screening of G-quadruplex DNA binding agents and telomerase inhibitors. This ECL sensor shows highly sensitive for detection of telomerase with the detection limit as low as 10 HeLa cells mL(-1)
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Telomerase
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|a EC 2.7.7.49
|2 NLM
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|a Wang, Jiasi
|e verfasserin
|4 aut
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|a Feng, Lingyan
|e verfasserin
|4 aut
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|a Ren, Jinsong
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|a Wei, Weili
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|a Qu, Xiaogang
|e verfasserin
|4 aut
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|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 24(2012), 18 vom: 08. Mai, Seite 2447-52
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|x 1521-4095
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|g volume:24
|g year:2012
|g number:18
|g day:08
|g month:05
|g pages:2447-52
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|u http://dx.doi.org/10.1002/adma.201200412
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