Superoxide dismutase, catalase and acetylcholinesterase : biomarkers for the joint effects of cadmium, zinc and methyl parathion contamination in water

Heavy metals are known to reduce the activities of antioxidant enzymes (e.g. superoxide dismutase, catalase), while organophosphorous insecticides are known to inhibit the activity of the enzyme acetylcholinesterase. In this study, the activities of these three enzymes in zebrafish (Danio rerio) tis...

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Veröffentlicht in:Environmental technology. - 1993. - 32(2011), 13-14 vom: 30. Okt., Seite 1463-70
1. Verfasser: Ling, XuePing (VerfasserIn)
Weitere Verfasser: Zhang, YiHeng, Lu, YingHua, Huang, HeQing
Format: Aufsatz
Sprache:English
Veröffentlicht: 2011
Zugriff auf das übergeordnete Werk:Environmental technology
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Biomarkers Drug Combinations Water Pollutants, Chemical Cadmium 00BH33GNGH Methyl Parathion 41BCL2O91D Catalase mehr... EC 1.11.1.6 Superoxide Dismutase EC 1.15.1.1 Acetylcholinesterase EC 3.1.1.7 Zinc J41CSQ7QDS
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520 |a Heavy metals are known to reduce the activities of antioxidant enzymes (e.g. superoxide dismutase, catalase), while organophosphorous insecticides are known to inhibit the activity of the enzyme acetylcholinesterase. In this study, the activities of these three enzymes in zebrafish (Danio rerio) tissues were assessed to evaluate the consequences heavy metal and organophosphate contamination in aquatic systems. When the fish were contacted with water containing a single pollutant, superoxide dismutase activity was affected by the presence of Cd but not by methyl parathion or Zn. However, catalase and acetylcholinesterase activities were sensitive to all three pollutants. The combined treatment showed that the three enzymes could be chosen as biomarkers of joint pollution by both metals and organophosphate. Toxicity tests showed an antagonism interaction between methyl parathion and Cd or Zn, and the change of enzyme activities at 96 hours was in accordance with that 
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700 1 |a Zhang, YiHeng  |e verfasserin  |4 aut 
700 1 |a Lu, YingHua  |e verfasserin  |4 aut 
700 1 |a Huang, HeQing  |e verfasserin  |4 aut 
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