Superoxide dismutase, catalase and acetylcholinesterase : biomarkers for the joint effects of cadmium, zinc and methyl parathion contamination in water
Heavy metals are known to reduce the activities of antioxidant enzymes (e.g. superoxide dismutase, catalase), while organophosphorous insecticides are known to inhibit the activity of the enzyme acetylcholinesterase. In this study, the activities of these three enzymes in zebrafish (Danio rerio) tis...
| Veröffentlicht in: | Environmental technology. - 1993. - 32(2011), 13-14 vom: 30. Okt., Seite 1463-70 |
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| Weitere Verfasser: | , , |
| Format: | Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2011
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| Zugriff auf das übergeordnete Werk: | Environmental technology |
| Schlagworte: | Journal Article Research Support, Non-U.S. Gov't Biomarkers Drug Combinations Water Pollutants, Chemical Cadmium 00BH33GNGH Methyl Parathion 41BCL2O91D Catalase mehr... |
| Zusammenfassung: | Heavy metals are known to reduce the activities of antioxidant enzymes (e.g. superoxide dismutase, catalase), while organophosphorous insecticides are known to inhibit the activity of the enzyme acetylcholinesterase. In this study, the activities of these three enzymes in zebrafish (Danio rerio) tissues were assessed to evaluate the consequences heavy metal and organophosphate contamination in aquatic systems. When the fish were contacted with water containing a single pollutant, superoxide dismutase activity was affected by the presence of Cd but not by methyl parathion or Zn. However, catalase and acetylcholinesterase activities were sensitive to all three pollutants. The combined treatment showed that the three enzymes could be chosen as biomarkers of joint pollution by both metals and organophosphate. Toxicity tests showed an antagonism interaction between methyl parathion and Cd or Zn, and the change of enzyme activities at 96 hours was in accordance with that |
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| Beschreibung: | Date Completed 14.03.2012 Date Revised 19.11.2015 published: Print Citation Status MEDLINE |
| ISSN: | 1479-487X |