DEEP-differential evolution entirely parallel method for gene regulatory networks

The Differential Evolution Entirely Parallel (DEEP) method is applied to the biological data fitting problem. We introduce a new migration scheme, in which the best member of the branch substitutes the oldest member of the next branch that provides a high speed of the algorithm convergence. We analy...

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Détails bibliographiques
Publié dans:The Journal of supercomputing. - 1998. - 57(2011), 2 vom: 01. Jan., Seite 172-178
Auteur principal: Kozlov, Konstantin (Auteur)
Autres auteurs: Samsonov, Alexander
Format: Article
Langue:English
Publié: 2011
Accès à la collection:The Journal of supercomputing
Sujets:Journal Article
Description
Résumé:The Differential Evolution Entirely Parallel (DEEP) method is applied to the biological data fitting problem. We introduce a new migration scheme, in which the best member of the branch substitutes the oldest member of the next branch that provides a high speed of the algorithm convergence. We analyze the performance and efficiency of the developed algorithm on a test problem of finding the regulatory interactions within the network of gap genes that control the development of early Drosophila embryo. The parameters of a set of nonlinear differential equations are determined by minimizing the total error between the model behavior and experimental observations. The age of the individuum is defined by the number of iterations this individuum survived without changes. We used a ring topology for the network of computational nodes. The computer codes are available upon request
Description:Date Revised 29.05.2025
published: Print
Citation Status PubMed-not-MEDLINE
ISSN:0920-8542