Effect of the β-propiolactone treatment on the adsorption and fusion of influenza A/Brisbane/59/2007 and A/New Caledonia/20/1999 virus H1N1 on a dimyristoylphosphatidylcholine/ganglioside GM3 mixed phospholipids monolayer at the air-water interface
The production protocol of many whole cell/virion vaccines involves an inactivation step with β-propiolactone (BPL). Despite the widespread use of BPL, its mechanism of action is poorly understood. Earlier work demonstrated that BPL alkylates nucleotide bases, but its interaction with proteins has n...
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Bibliographische Detailangaben
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1992. - 27(2011), 22 vom: 15. Nov., Seite 13675-83
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| 1. Verfasser: |
Desbat, Bernard
(VerfasserIn) |
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| Weitere Verfasser: |
Lancelot, Eloïse,
Krell, Tino,
Nicolaï, Marie-Claire,
Vogel, Fred,
Chevalier, Michel,
Ronzon, Frédéric |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2011
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
G(M3) Ganglioside
Water
059QF0KO0R
Propiolactone
6RC3ZT4HB0
Dimyristoylphosphatidylcholine
U86ZGC74V5 |
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