|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM211426792 |
| 003 |
DE-627 |
| 005 |
20231224013523.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231224s2012 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1007/s10646-011-0785-z
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n0705.xml
|
| 035 |
|
|
|a (DE-627)NLM211426792
|
| 035 |
|
|
|a (NLM)21912977
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Li, Xiao-Yu
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Acute toxicity and responses of antioxidant systems to 1-methyl-3-octylimidazolium bromide at different developmental stages of goldfish
|
| 264 |
|
1 |
|c 2012
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 24.04.2012
|
| 500 |
|
|
|a Date Revised 20.10.2021
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a Acute toxicity of 1-methyl-3-octylimidazolium bromide ([C(8)mim]Br) to goldfish at different developmental stages and responses of the antioxidant system in adult goldfish were evaluated in the present study. The results indicate that post-embryonic developmental toxicity of [C(8)mim]Br on goldfish is developmental-stage dependent. The juvenile and larva goldfish are more sensitive to [C(8)mim]Br-toxicity than the adult fish. Histological observations in adult goldfish reveal that acute [C(8)mim]Br exposure damages the hepatopancreas, intestines, and kidneys, indicating that these are possible target organs of [C(8)mim]Br toxicity in goldfish. Subsequent biochemical assays in adult goldfish show that [C(8)mim]Br also induces changes in the activities of the superoxide dismutase, catalase, glutathione peroxidase, and glutathione content of fish hepatopancreas. These results suggest that [C(8)mim]Br exposure may induce oxidant stress and lipid peroxidation in hepatopancreas of adult goldfish. In addition, we also find that [C(8)mim]Br causes a remarkable increase in malondialdehyde (MDA) levels in the hepatopancreas of adult goldfish, and thus we think that the MDA level change can be a biomarker of [C(8)mim]Br toxicity in goldfish. The present study indicates that ionic liquids can be a threat to the survival, growth, and development of the fish population once they are accidentally leaked into aquatic ecosystems
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Research Support, Non-U.S. Gov't
|
| 650 |
|
7 |
|a 1-methyl-3-octylimidazolium bromide
|2 NLM
|
| 650 |
|
7 |
|a Antioxidants
|2 NLM
|
| 650 |
|
7 |
|a Imidazoles
|2 NLM
|
| 650 |
|
7 |
|a Ionic Liquids
|2 NLM
|
| 650 |
|
7 |
|a Malondialdehyde
|2 NLM
|
| 650 |
|
7 |
|a 4Y8F71G49Q
|2 NLM
|
| 650 |
|
7 |
|a Catalase
|2 NLM
|
| 650 |
|
7 |
|a EC 1.11.1.6
|2 NLM
|
| 650 |
|
7 |
|a Glutathione Peroxidase
|2 NLM
|
| 650 |
|
7 |
|a EC 1.11.1.9
|2 NLM
|
| 650 |
|
7 |
|a Superoxide Dismutase
|2 NLM
|
| 650 |
|
7 |
|a EC 1.15.1.1
|2 NLM
|
| 650 |
|
7 |
|a Glutathione
|2 NLM
|
| 650 |
|
7 |
|a GAN16C9B8O
|2 NLM
|
| 700 |
1 |
|
|a Zeng, Shi-Hu
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Dong, Xiang-Yi
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Ma, Jun-Guo
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Wang, Jian-Ji
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Ecotoxicology (London, England)
|d 1992
|g 21(2012), 1 vom: 05. Jan., Seite 253-9
|w (DE-627)NLM098212214
|x 1573-3017
|7 nnns
|
| 773 |
1 |
8 |
|g volume:21
|g year:2012
|g number:1
|g day:05
|g month:01
|g pages:253-9
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1007/s10646-011-0785-z
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_65
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 21
|j 2012
|e 1
|b 05
|c 01
|h 253-9
|