Modification of proteins with cyclodextrins prevents aggregation and surface adsorption and increases thermal stability
This work describes a general approach for preventing protein aggregation and surface adsorption by modifying proteins with β-cyclodextrins (βCD) via an efficient water-driven ligation. As compared to native unmodified proteins, the cyclodextrin-modified proteins (lysozyme and RNase A) exhibit signi...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1992. - 27(2011), 21 vom: 01. Nov., Seite 13091-6
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| 1. Verfasser: |
Prashar, Deepali
(VerfasserIn) |
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| Weitere Verfasser: |
Cui, DaWei,
Bandyopadhyay, Debjyoti,
Luk, Yan-Yeung |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2011
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Cyclodextrins
Water
059QF0KO0R
Ribonuclease, Pancreatic
EC 3.1.27.5
Muramidase
EC 3.2.1.17
Lysine
K3Z4F929H6 |
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