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231223s2011 xx |||||o 00| ||eng c |
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|a 10.1021/la1041019
|2 doi
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|a pubmed24n0685.xml
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|a (DE-627)NLM205579175
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|a (NLM)21291255
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a eng
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1 |
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|a Fuchigami, Teruaki
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Ferromagnetic FePt-nanoparticles/polycation hybrid capsules designed for a magnetically guided drug delivery system
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|c 2011
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| 336 |
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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| 338 |
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 21.10.2014
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|a Date Revised 09.12.2020
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a The present Article describes the synthesis of ferromagnetic capsules approximately 330 nm in diameter with a nanometer-thick shell to apply to magnetic carriers in a magnetically guided drug delivery system. The magnetic shell of 5 nm in thickness is a nanohybrid, composed of ordered alloy FePt nanoparticles of approximately 3-4 nm in size and a polymer layer of a cationic polyelectrolyte, poly(diaryldimethylammonium chloride) (PDDA). The magnetic capsules have an excellent capacity for carrying medical drugs and genes. Surface-modified silica particles with PDDA were used as a template for the capsules. FePt nanoparticles were deposited on the PDDA-modified silica particles through a polyol method followed by dissolving the silica particles with a NaOH solution, resulting in the formation of the magnetic capsules as the final product. A three-dimensional hollow structure is maintained by the nanohybrid shell. The FePt-nanoparticles/PDDA nanohybrid shell also exhibits a ferromagnetic feature at room temperature because the FePt nanoparticles of an ordered-alloy phase are formed with the aid of PDDA despite the small size (3-4 nm)
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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7 |
|a Capsules
|2 NLM
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7 |
|a Polyamines
|2 NLM
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|a Polyelectrolytes
|2 NLM
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| 650 |
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7 |
|a polycations
|2 NLM
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| 650 |
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7 |
|a Platinum
|2 NLM
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| 650 |
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7 |
|a 49DFR088MY
|2 NLM
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| 650 |
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7 |
|a Iron
|2 NLM
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| 650 |
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7 |
|a E1UOL152H7
|2 NLM
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| 700 |
1 |
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|a Kawamura, Ryo
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kitamoto, Yoshitaka
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Nakagawa, Masaru
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Namiki, Yoshihisa
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 27(2011), 6 vom: 15. März, Seite 2923-8
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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| 773 |
1 |
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|g volume:27
|g year:2011
|g number:6
|g day:15
|g month:03
|g pages:2923-8
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|u http://dx.doi.org/10.1021/la1041019
|3 Volltext
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