An X-ray spectromicroscopy study of protein adsorption to polystyrene-poly(ethylene oxide) blends

Synchrotron-based X-ray photoemission electron microscopy (X-PEEM) and atomic force microscopy (AFM) were used to characterize the composition and surface morphology of thin films of a polystyrene-poly(ethylene oxide) blend (PS-PEO), spun cast from dichloromethane at various mass ratios and polymer...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 26(2010), 18 vom: 21. Sept., Seite 14759-65
1. Verfasser: Leung, Bonnie O (VerfasserIn)
Weitere Verfasser: Hitchcock, Adam P, Brash, John L, Scholl, Andreas, Doran, Andrew
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2010
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Polystyrenes Proteins Polyethylene Glycols 3WJQ0SDW1A
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520 |a Synchrotron-based X-ray photoemission electron microscopy (X-PEEM) and atomic force microscopy (AFM) were used to characterize the composition and surface morphology of thin films of a polystyrene-poly(ethylene oxide) blend (PS-PEO), spun cast from dichloromethane at various mass ratios and polymer concentrations. X-PEEM reveals incomplete segregation with ∼30% of PS in the PEO region and vice versa. Protein (human serum albumin) adsorption studies show that this partial phase separation leads to greater protein repellency in the PS region, whereas more protein is detected in the PEO region compared to control samples 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Research Support, U.S. Gov't, Non-P.H.S. 
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650 7 |a Polyethylene Glycols  |2 NLM 
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700 1 |a Hitchcock, Adam P  |e verfasserin  |4 aut 
700 1 |a Brash, John L  |e verfasserin  |4 aut 
700 1 |a Scholl, Andreas  |e verfasserin  |4 aut 
700 1 |a Doran, Andrew  |e verfasserin  |4 aut 
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