Chemoselective immobilization of peptides on abiotic and cell surfaces at controlled densities

We report herein a new and enabling approach for decorating both abiotic and cell surfaces with the extracellular matrix IKVAV peptide in a site-specific manner using strain promoted azide-alkyne cycloaddition. A cyclooctyne-derivatized IKVAV peptide was synthesized and immobilized on the surface of...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 26(2010), 11 vom: 01. Juni, Seite 7675-8
1. Verfasser: Krishnamurthy, Venkata R (VerfasserIn)
Weitere Verfasser: Wilson, John T, Cui, Wanxing, Song, XueZheng, Lasanajak, Yi, Cummings, Richard D, Chaikof, Elliot L
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2010
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Peptides