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231223s2010 xx |||||o 00| ||eng c |
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|a 10.1021/la904375k
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|a eng
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| 100 |
1 |
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|a Chen, Ning
|e verfasserin
|4 aut
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|a Thermo-switching of the conformation of genomic DNA in solutions of poly(N-isopropylacrylamide)
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|c 2010
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|a Date Completed 28.05.2010
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|a Date Revised 23.02.2010
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|a published: Print
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|a Citation Status MEDLINE
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|a We used poly(N-isopropylacrylamide) (PNIPAM) to control the conformation of genomic DNA by changing the temperature of a reaction solution and studied the DNA transition at the level of single DNA molecules. With this method, the conformation of long genomic DNA can be readily and reversibly switched between a very compact condensate and an unfolded macromolecule
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|a Journal Article
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|a Zinchenko, Anatoly A
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|a Kidoaki, Satoru
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|a Murata, Shizuaki
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|a Yoshikawa, Kenichi
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