A dual-activation, adenoviral-based system for the controlled induction of DNA double-strand breaks by the restriction endonuclease SacI
Spontaneous damage to DNA is frequent and may lead to cell death, cell senescence, or mutations. DNA double-strand breaks (DSBs) are of special interest because they are highly toxic and have been implicated in neurodegeneration, cancer, and aging. Until now, there has not been a reliable system all...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | BioTechniques. - 1991. - 47(2009), 4 vom: 23. Okt., Seite 847-54
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| 1. Verfasser: |
Maslov, Alexander Y
(VerfasserIn) |
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| Weitere Verfasser: |
Metrikin, Maya,
Vijg, Jan |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2009
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| Zugriff auf das übergeordnete Werk: | BioTechniques
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| Schlagworte: | Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Anti-Bacterial Agents
Coloring Agents
Selective Estrogen Receptor Modulators
Tetrazolium Salts
Thiazoles
Tamoxifen
094ZI81Y45
mehr...
DNA
9007-49-2
endodeoxyribonuclease SacI
EC 3.1.21.-
Deoxyribonucleases, Type II Site-Specific
EC 3.1.21.4
thiazolyl blue
EUY85H477I
Doxycycline
N12000U13O |
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