A dual-activation, adenoviral-based system for the controlled induction of DNA double-strand breaks by the restriction endonuclease SacI
Spontaneous damage to DNA is frequent and may lead to cell death, cell senescence, or mutations. DNA double-strand breaks (DSBs) are of special interest because they are highly toxic and have been implicated in neurodegeneration, cancer, and aging. Until now, there has not been a reliable system all...
Description complète
Détails bibliographiques
Publié dans: | BioTechniques. - 1991. - 47(2009), 4 vom: 23. Okt., Seite 847-54
|
Auteur principal: |
Maslov, Alexander Y
(Auteur) |
Autres auteurs: |
Metrikin, Maya,
Vijg, Jan |
Format: | Article en ligne
|
Langue: | English |
Publié: |
2009
|
Accès à la collection: | BioTechniques
|
Sujets: | Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Anti-Bacterial Agents
Coloring Agents
Selective Estrogen Receptor Modulators
Tetrazolium Salts
Thiazoles
Tamoxifen
094ZI81Y45
plus...
DNA
9007-49-2
endodeoxyribonuclease SacI
EC 3.1.21.-
Deoxyribonucleases, Type II Site-Specific
EC 3.1.21.4
thiazolyl blue
EUY85H477I
Doxycycline
N12000U13O |