Estradiol targets T cell signaling pathways in human systemic lupus

The major risk factor for developing systemic lupus erythematosus (SLE) is being female. The present study utilized gene profiles of activated T cells from females with SLE and healthy controls to identify signaling pathways uniquely regulated by estradiol that could contribute to SLE pathogenesis....

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 133(2009), 3 vom: 01. Dez., Seite 428-36
1. Verfasser: Walters, Emily (VerfasserIn)
Weitere Verfasser: Rider, Virginia, Abdou, Nabih I, Greenwell, Cindy, Svojanovsky, Stan, Smith, Peter, Kimler, Bruce F
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Adaptor Proteins, Signal Transducing Carrier Proteins IFIT1 protein, human MED14 protein, human Mediator Complex RNA, Messenger RNA-Binding Proteins Estradiol 4TI98Z838E