Metabonomic investigations into the global biochemical sequelae of exposure to the pancreatic toxin 1-cyano-2-hydroxy-3-butene in the rat

The time-related metabolic effects of 1-cyano-2-hydroxy-3-butene (CHB, crambene), a naturally occurring nitrile and experimental model toxin causing exocrine pancreatitis, have been investigated in rats using high-resolution NMR spectroscopy of urine and serum in combination with pattern recognition...

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Veröffentlicht in:Magnetic resonance in chemistry : MRC. - 1985. - 47 Suppl 1(2009) vom: 01. Dez., Seite S26-35
1. Verfasser: Bohus, Eszter (VerfasserIn)
Weitere Verfasser: Rácz, Akos, Noszál, Béla, Coen, Muireann, Beckonert, Olaf, Keun, Hector C, Ebbels, Timothy M D, Cantor, Glenn H, Wijsman, John A, Holmes, Elaine, Lindon, John C, Nicholson, Jeremy K
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Magnetic resonance in chemistry : MRC
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Alkenes Nitriles 1-cyano-2-hydroxy-3-butene 27451-36-1