Beta-galactosylceramide alters invariant natural killer T cell function and is effective treatment for lupus

NZB/W female mice spontaneously develop systemic lupus, an autoantibody mediated disease associated with immune complex glomerulonephritis. Natural killer (NK) T cells augment anti-dsDNA antibody secretion by NZB/W B cells in vitro, and blocking NKT cell activation in vivo with anti-CD1 mAb ameliora...

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Publié dans:	Clinical immunology (Orlando, Fla.). - 1999. - 132(2009), 3 vom: 03. Sept., Seite 321-33
Auteur principal:	Morshed, Sufi R (Auteur)
Autres auteurs:	Takahashi, Tsuyoshi, Savage, Paul B, Kambham, Neeraja, Strober, Samuel
Format:	Article en ligne
Langue:	English
Publié:	2009
Accès à la collection:	Clinical immunology (Orlando, Fla.)
Sujets:	Journal Article Antibodies, Antinuclear Antigens, CD1d Ceramides Monosaccharides Receptors, Antigen, T-Cell Receptors, Antigen, T-Cell, alpha-beta beta-galactosyl ceramide Interleukin-4 207137-56-2 plus... Interferon-gamma 82115-62-6