CD4+ T cell dysfunction in subjects with chronic HIV infection is in part due to an imbalance of costimulatory and coinhibitory receptors. We report that virus-specific CD4+ T cells expressing 4-1BB (CD137) or OX40 (CD134) produced more IL-2 than cells lacking these costimulatory receptors (P<0.0...
Bibliographische Detailangaben
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 132(2009), 2 vom: 15. Aug., Seite 234-45
|
|---|
| 1. Verfasser: |
Kassu, Afework
(VerfasserIn) |
|---|
| Weitere Verfasser: |
D'Souza, Michelle,
O'Connor, Brian P,
Kelly-McKnight, Elizabeth,
Akkina, Ramesh,
Fontenot, Andrew P,
Palmer, Brent E |
|---|
| Format: | Online-Aufsatz
|
|---|
| Sprache: | English |
|---|
| Veröffentlicht: |
2009
|
|---|
| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.)
|
|---|
| Schlagworte: | Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
4-1BB Ligand
Interleukin-2
OX40 Ligand
Receptors, OX40
TNFRSF4 protein, human
TNFRSF9 protein, human
Tumor Necrosis Factor Receptor Superfamily, Member 9
mehr...
Interferon-gamma
82115-62-6 |
|---|