|
|
|
|
| LEADER |
01000caa a22002652 4500 |
| 001 |
NLM187884536 |
| 003 |
DE-627 |
| 005 |
20250210083219.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231223s2009 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1002/mrc.2427
|2 doi
|
| 028 |
5 |
2 |
|a pubmed25n0626.xml
|
| 035 |
|
|
|a (DE-627)NLM187884536
|
| 035 |
|
|
|a (NLM)19373771
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Capacchi, Silvia
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a 1H NMR discrimination of CHF4226.01 diastereoisomers in DMSO-d6
|
| 264 |
|
1 |
|c 2009
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 12.08.2009
|
| 500 |
|
|
|a Date Revised 20.11.2014
|
| 500 |
|
|
|a published: Print
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a 2009 John Wiley & Sons, Ltd.
|
| 520 |
|
|
|a Two diastereoisomers CHF4226.01 (R, R) and CHF4232.01 (S, R), differing for a chiral center, have been studied to investigate their possible discrimination using NMR. 1D NMR and 2D NMR experiments, such as COSY, NOESY and ROESY, were performed on pure isomers and on the association complexes formed in the presence of the chiral reagent (S)-(-)-1-(2-napthyl)ethylamine (S-NEA). Moreover, computational studies, concerning conformational analysis and molecular dynamics, were started and supported the NMR results
|
| 650 |
|
4 |
|a Comparative Study
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
7 |
|a Amphetamines
|2 NLM
|
| 650 |
|
7 |
|a Bronchodilator Agents
|2 NLM
|
| 650 |
|
7 |
|a Hydroxyquinolines
|2 NLM
|
| 650 |
|
7 |
|a carmoterol
|2 NLM
|
| 650 |
|
7 |
|a 9810NUL4D1
|2 NLM
|
| 650 |
|
7 |
|a Dimethyl Sulfoxide
|2 NLM
|
| 650 |
|
7 |
|a YOW8V9698H
|2 NLM
|
| 700 |
1 |
|
|a Lipreri, Milco
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Rizzi, Andrea
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Caló, Claudia
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Peveri, Tiziana
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Catinella, Silvia
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Magnetic resonance in chemistry : MRC
|d 1985
|g 47(2009), 7 vom: 15. Juli, Seite 551-61
|w (DE-627)NLM098179667
|x 1097-458X
|7 nnns
|
| 773 |
1 |
8 |
|g volume:47
|g year:2009
|g number:7
|g day:15
|g month:07
|g pages:551-61
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1002/mrc.2427
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 47
|j 2009
|e 7
|b 15
|c 07
|h 551-61
|